SrasV1, Main, Exploration, bibRecord, 004550

[Cloning of ACE-2 gene encoding the functional receptor for the SARS coronavirus and its expression in eukaryotic cells].

Identifieur interne : 004550 ( Main/Exploration ); précédent : 004549; suivant : 004551

[Cloning of ACE-2 gene encoding the functional receptor for the SARS coronavirus and its expression in eukaryotic cells].

Auteurs : Jian Lu [République populaire de Chine] ; Bai-Ping Zhou ; Li-Xia Wen ; Xiao-Ling Jiang

Source :

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology [ 1003-9279 ] ; 2005.

RBID : pubmed:16261211

Descripteurs français

KwdFr :
- Animaux, Cellules Vero, Clonage moléculaire, Expression des gènes, Humains, Lignée cellulaire, Peptidyl-Dipeptidase A (génétique), Peptidyl-Dipeptidase A (immunologie), Peptidyl-Dipeptidase A (métabolisme), Plasmides (génétique), RT-PCR, Récepteurs viraux (génétique), Récepteurs viraux (immunologie), Récepteurs viraux (métabolisme), Technique de Western, Tests de neutralisation, Transfection, Virus du SRAS (immunologie), Virus du SRAS (métabolisme).
MESH :
- génétique : Peptidyl-Dipeptidase A, Plasmides, Récepteurs viraux.
- immunologie : Peptidyl-Dipeptidase A, Récepteurs viraux, Virus du SRAS.
- métabolisme : Peptidyl-Dipeptidase A, Récepteurs viraux, Virus du SRAS.
- Animaux, Cellules Vero, Clonage moléculaire, Expression des gènes, Humains, Lignée cellulaire, RT-PCR, Technique de Western, Tests de neutralisation, Transfection.

English descriptors

KwdEn :
- Animals, Blotting, Western, Cell Line, Chlorocebus aethiops, Cloning, Molecular, Gene Expression, Humans, Neutralization Tests, Peptidyl-Dipeptidase A (genetics), Peptidyl-Dipeptidase A (immunology), Peptidyl-Dipeptidase A (metabolism), Plasmids (genetics), Receptors, Virus (genetics), Receptors, Virus (immunology), Receptors, Virus (metabolism), Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (immunology), SARS Virus (metabolism), Transfection, Vero Cells.
MESH :
- chemical , genetics : Peptidyl-Dipeptidase A, Receptors, Virus.
- chemical , immunology : Peptidyl-Dipeptidase A, Receptors, Virus.
- chemical , metabolism : Peptidyl-Dipeptidase A, Receptors, Virus.
- genetics : Plasmids.
- immunology : SARS Virus.
- metabolism : SARS Virus.
- Animals, Blotting, Western, Cell Line, Chlorocebus aethiops, Cloning, Molecular, Gene Expression, Humans, Neutralization Tests, Reverse Transcriptase Polymerase Chain Reaction, Transfection, Vero Cells.

Abstract

Angiotensin-converting enzyme 2 (ACE-2) has been identified as a functional receptor of severe acute respiratory syndrome coronavirus (SARS-CoV), so its gene was cloned and eukaryotic expressed for further insight into mechanisms in SARS-CoV entry and pathogenesis, as well as development of a safe and reliable neutralization assay for SARS-CoV.

PubMed: 16261211

Affiliations:

Le document en format XML

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<author><name sortKey="Zhou, Bai Ping" sort="Zhou, Bai Ping" uniqKey="Zhou B" first="Bai-Ping" last="Zhou">Bai-Ping Zhou</name>
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<author><name sortKey="Wen, Li Xia" sort="Wen, Li Xia" uniqKey="Wen L" first="Li-Xia" last="Wen">Li-Xia Wen</name>
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<term>Cloning, Molecular</term>
<term>Gene Expression</term>
<term>Humans</term>
<term>Neutralization Tests</term>
<term>Peptidyl-Dipeptidase A (genetics)</term>
<term>Peptidyl-Dipeptidase A (immunology)</term>
<term>Peptidyl-Dipeptidase A (metabolism)</term>
<term>Plasmids (genetics)</term>
<term>Receptors, Virus (genetics)</term>
<term>Receptors, Virus (immunology)</term>
<term>Receptors, Virus (metabolism)</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>SARS Virus (immunology)</term>
<term>SARS Virus (metabolism)</term>
<term>Transfection</term>
<term>Vero Cells</term>
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<term>Cellules Vero</term>
<term>Clonage moléculaire</term>
<term>Expression des gènes</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Peptidyl-Dipeptidase A (génétique)</term>
<term>Peptidyl-Dipeptidase A (immunologie)</term>
<term>Peptidyl-Dipeptidase A (métabolisme)</term>
<term>Plasmides (génétique)</term>
<term>RT-PCR</term>
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<term>Récepteurs viraux (immunologie)</term>
<term>Récepteurs viraux (métabolisme)</term>
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<term>Transfection</term>
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<term>Virus du SRAS (métabolisme)</term>
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<term>Récepteurs viraux</term>
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<term>Récepteurs viraux</term>
<term>Virus du SRAS</term>
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<term>Virus du SRAS</term>
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<term>Cell Line</term>
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<term>Neutralization Tests</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
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<term>Humains</term>
<term>Lignée cellulaire</term>
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<term>Tests de neutralisation</term>
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<front><div type="abstract" xml:lang="en">Angiotensin-converting enzyme 2 (ACE-2) has been identified as a functional receptor of severe acute respiratory syndrome coronavirus (SARS-CoV), so its gene was cloned and eukaryotic expressed for further insight into mechanisms in SARS-CoV entry and pathogenesis, as well as development of a safe and reliable neutralization assay for SARS-CoV.</div>
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<tree><noCountry><name sortKey="Jiang, Xiao Ling" sort="Jiang, Xiao Ling" uniqKey="Jiang X" first="Xiao-Ling" last="Jiang">Xiao-Ling Jiang</name>
<name sortKey="Wen, Li Xia" sort="Wen, Li Xia" uniqKey="Wen L" first="Li-Xia" last="Wen">Li-Xia Wen</name>
<name sortKey="Zhou, Bai Ping" sort="Zhou, Bai Ping" uniqKey="Zhou B" first="Bai-Ping" last="Zhou">Bai-Ping Zhou</name>
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Serveur d'exploration SRAS

[Cloning of ACE-2 gene encoding the functional receptor for the SARS coronavirus and its expression in eukaryotic cells].

[Cloning of ACE-2 gene encoding the functional receptor for the SARS coronavirus and its expression in eukaryotic cells].

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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